Biotechnology

• Fellow: WB Acad. of Sc. & Tech

Journal
• Apoptosis-inducing factor-like protein-mediated stress and metronidazole-responsive programmed cell death pathway in Entamoeba histolytica Bandyopadhyay A., Ghosh S.K. By Molecular Microbiology 119 640-658 (2023)
• Three-amino acid loop extension homeodomain proteins regulate stress responses and encystation in Entamoeba Meenakshi .., Balbhim S. S., Sarkar S. , Vasudevan M. , Ghosh S. K. By Molecular Microbiology 1-22 (2023)
• Stress-responsive AMP Kinase like protein regulates encystation of Entamoeba invadens Goswami P., Samanta S. K., Agarwal T. , Ghosh S. K. By Molecular and Biochemical Parasitology 251 111507- (2022)
• A potent antibiotic-loaded bone-cement implant against staphylococcal bone infections Ghosh S., Sinha M. , Samanta R. , Sadhasivam S. , Bhattacharyya A. , Nandy A. , Saini S. , Tandon N. , Singh H. , Gupta S. , Chauhan A. , Aavula K. K., Varghese S. S., Shi P. , Ghosh S. K., Garg M. ., Saha T. , Padhye A. , Ghosh S. , Jang H. L., Sengupta S. By Nature Biomedical Engineering 6 1180-1195 (2022)
• Recent advances in bioprinting technologies for engineering hepatic tissue Agarwal T., Banerjee D., Konwarh R., Esworthy T., Kumari J., Onesto V., Das P., Lee B.H., Wagener F.A.D.T.G., Makvandi P., Mattoli V., Ghosh S.K., Maiti T.K., Zhang L.G., Ozbolat I.T. By Materials Science and Engineering C 123 - (2021)
• Development of marker-free transgenic pigeon pea (Cajanus cajan) expressing a pod borer insecticidal protein Sarkar S., Roy S., Ghosh S.K. By Scientific Reports 11 - (2021)
• Dual Functionalized Injectable Hybrid Extracellular Matrix Hydrogel for Burn Wounds Bankoti K., Rameshbabu A.P., Datta S., Goswami P., Roy M., Das D., Ghosh S.K., Das A.K., Mitra A., Pal S., Maulik D., Su B., Ghosh P., Basu B., Dhara S. By Biomacromolecules 22 514-533 (2021)
• Carbon nanodot decorated acellular dermal matrix hydrogel augments chronic wound closure Bankoti K., Rameshbabu A.P., Datta S., Roy M., Goswami P., Roy S., Das A.K., Ghosh S.K., Dhara S. By Journal of Materials Chemistry B 8 9277-9294 (2020)
• Morphological and motility features of the stable bleb driven monopodial form of Entamoeba and its importance in encystation Krishnan D., Ghosh S. K. By Infection and Immunity 88 1-25 (2020)
• Thiol stabilized copper nanoparticles exert antimicrobial properties by preventing cell division in Escherichia coli Kumar N. G., Pandey S. D., Mallick S. , Ghosh S. K., Pramanik P. , Ghosh A. S. By Indian Journal of Biochemistry and Biophysics (IJBB) 57 151-157 (2020)
• Inexpensive and Versatile Paper-Based Platform for 3D Culture of Liver Cells and Related Bioassays Agarwal T., Biswas P., Pal S., Maiti T.K., Chakraborty S., Ghosh S.K., Dhar R. By ACS Applied Bio Materials 3 2522-2533 (2020)
• Inexpensive and Versatile Paper-Based Platform for 3D Culture of Liver Cells and Related Bioassays. Agarwal T., Biswas P. , Pal S. , Maiti T. K., Chakraborty S. , Ghosh S. K., Dhar R. By ACS Applied Bio Materials 3 2522-2533 (2020)
• Bio-surfactin stabilised silver nanoparticles exert inhibitory effect over New-Delhi metallo-beta-lactamases (NDMs) and the cells harbouring NDMs Kumar G., Kumar G. , Mallick S. , Ghosh S. K., Pramanik P. , Ghosh A. S. By FEMS Microbiology Letters 366 118- (2019)
• Decellularized caprine liver-derived biomimetic and pro-angiogenic scaffolds for liver tissue engineering Agarwal T., Maiti T. K., Ghosh S. K. By Mater Sci Eng C Mater Biol Appl. 98 939-948 (2019)
• Nucleotide sugar transporters of Entamoeba histolytica and Entamoeba invadens involved in chitin synthesis Nayak S., Ghosh S. K. By Molecular Biochemical Parasitology 234 1-11 (2019)
• Prevention of epithelial to mesenchymal transition in colorectal carcinoma by regulation of the E-cadherin- -catenin-vinculin axis. Pal I., Rajesh Y. , Banik P. , Dey G. , Dey K. K., Bharti R. , Naskar D. , Chakraborty S. , Ghosh S. K., Das S. K., Emdad L. , Kundu S. C., Fisher P. B., Mandal M. By Cancer Letters 252 254-263 (2019)
• Application of lateral branching to overcome the recalcitrance of in vitro regeneration of Agrobacterium-infected pigeonpea (Cajanus cajan L.) Sarkar S., Roy S., Ghosh S.K., Basu A. By Plant Cell, Tissue and Organ Culture 137 23-32 (2019)
• Targeting NFE2L2, a transcription factor upstream of MMP-2: A potential therapeutic strategy for temozolomide resistant glioblastoma. Rajesh Y., A B. , U K. , S D. , Banerjee I. , Banik P. , Bharti R. , Nayak S. , Ghosh S. K., Mandal M. By Biochem Pharmacology 164 1-16 (2019)
• Stress-responsive Entamoeba Topoisomerase II: A Potential Antiamoebic Target Varghese S. S., Ghosh S. K. By FEBS Letter 1-16 (2019)
• Single-pot biofabrication of living fibers for tissue engineering applications Ghosh P., Rameshbabu A. P., Das D. , Subramanian B. , Samanta S. K., Roy S. , Pal S. , Ghosh S. K., Dhara S. By J Mat. Res 33 2019-2028 (2018)
• Identification and functional analysis of a stress-responsive MAPK15 in Entamoeba invadens. Singh T., Agarwal T. , Ghosh S. K. By Mol Biochem Parasitol 222 34-44 (2018)
• Decellularized caprine liver extracellular matrix as a 2D substrate coating and 3D hydrogel platform for vascularized liver tissue engineering Agrawal T., Narayan R. , Maji S. , Ghosh S. K., Maiti T. K. By J Tissue Eng Regen Med. 12 678-690 (2018)
• Cellular Events of Multinucleated Giant Cells Formation During the Encystation of Entamoeba invadens Krishnan D., Ghosh S. K. By Front Cell Infect Microbiol 8 1-13 (2018)
• A novel encystation specific protein kinase regulates chitin synthesis in Entamoeba invadens Samanta S. K., Varghese S. S., Krishnan D. , Baidya M. , Nayak D. , Mukherjee S. , Ghosh S. K. By Mol Biochem Parasitol. 220 19-27 (2018)
• Accelerated healing of full thickness dermal wounds by macroporous waterborne polyurethane-chitosan hydrogel scaffolds. Bankoti K., Rameshbabu A. P., Datta S. , Maity P. P., Goswami P. , Dutta P. , Ghosh S. K., Mitra A. , Dhara S. By Mater Sci Eng C Mater Biol Appl. 81 133-143 (2017)
• Molecular Mechanisms Associated With Particulate and Soluble Heteroglycan Mediated Immune Response Devi K. S., Krishna D. , Das J. , Agarwal T. , Kumari K. , Maji S. , Ghosh S. K., Maiti T. K. By Journal of Cellular Biochemistry 117 1580-1593 (2016)
• In Vitro Drug and gene Delivery Using Random Cationic Copolymers Forming Stable and pH-Sensitive Polymersomes Laskar P., Dey J. , Banik P. , Mandal M. , Ghosh S. K. By Macromol. Biosci. 17 1-14 (2016)
• DNA damaging, cell cytotoxicity and serum albumin binding efficacy of the rutin-Cu(II) complex Singha Roy A., Tripathy D. , Samanta S. , Ghosh S. K., Dasgupta S. By Mol. BioSyst. 12 1687-1701 (2016)
• Carbon Dots Embedded Magnetic Nanoparticles @Chitosan @Metal Organic Framework as a Nanoprobe for pH Sensitive Targeted Anticancer Drug Delivery Ray Chowdhuri A., Singh T. , Ghosh S. K., Sahu S. K. By ACS Appl. Mater. Interfaces 8 16573-16583 (2016)
• Cell cytotoxicity and serum albumin binding capacity of the morin-Cu(II) complex and its effect on deoxyribonucleic acid Singha Roy A., Samanta S. , Ghosh P. , Tripathy D. , Ghosh S. K., Dasgupta S. By Mol. BioSyst. 12 2818-2833 (2016)
• Highly Hydrophilic Luminescent Magnetic Mesoporous Carbon Nanospheres for Controlled Release of Anticancer Drug and Multimodal Imaging Mohapatra S., Rout S. R., Das R. K., Nayak S. , Ghosh S. K. By Langmuir 32 1611-1620 (2016)
• PEG based random copolymer micelles as drug carriers: Effect of hydrophobe content on drug solubilization and cytotoxicity Laskar P, Saha B, Ghosh SK and Dey J By RSC Advance 5 16265-16276 (2015)
• Design of Fe3O4@SiO2@Carbon Quantum Dot Based Nanostructure for Fluorescence Sensing, Magnetic Separation and Live Cell Imaging of Fluoride Ion Mohapatra S, Sahu S, Nayak S, and Ghosh SK By Langmuir 31 8111-8120 (2015)
• Assessing the role of an immunomodulatory heteroglycan in a tumor spheroid and macrophage co-culture model system K. Sanjana P Devi, Mishra D, Roy B, Ghosh SK and Maiti TK By Carbohydrate Polymers 127 1-10 (2015)
• The chitin biosynthesis pathway in Entamoeba and the role of Glucosamin-6-P isomerase by RNA interference Samanta SK and Ghosh SK By Mol. Biochem. Parasitol 186 60-68 (2012)
• The Jacob2 lectin of the Entamoeba histolytica cyst wall binds chitin and is polymorphic Ghosh SK, Van dellen K, Chatterjee A, Dey T, Haque R, Robbins PW and Samuelson J By PLoS Neg. Diseases 4 - (2010)
• Entamoeba invadens: Cloning and molecular characterization of Chitinases Dey T, Basu R and Ghosh SK By Experimental Parasitology 123 244-9 (2009)
• Evidence for a "wattle and daub" model of the cyst wall of entamoeba Chatterjee A., Ghosh S. K., Jang K, Bullitt E, Moore L, Robbins Pw, Samuelson J ,. By PLoS Pathog 5 - (2009)
• Giardia, Entamoeba,Trichomonas enzymes activate metronidazole (nitroreductase) and inactivate metronidazole (NIMs) Pal D, Banerjee S, Cui J, Swartz A, Ghosh SK and Samuelson J By Antimicrobial Agent Chemotherapy 53 458-64 (2009)
• Hsp60 is targeted to a cryptic mitochondrion-derived organelle (crypton ) in the microaerophilic protozoan parasite Entamoeba histolytica Mai Z, Ghosh SK, Frisardi M, Rogers R and Samuelson J By Mol. Cell Biol 19 2198-2205 (1999)
• Overexpression of P glycoprotein gene1 by transfected Entamoeba histolytica confers emetine-resistance. Ghosh SK, Lohia A, Kumar A andSamuelson J By Mol Biochem Parasitol 82 257-60 (1996)
Workshop
• Exploring direct bioethanol production in green alga Chlorella vulgaris through transgenic strategies Saha S., Chatterjee A. , Ghosh S. K., Maiti M. K. By DBT National Workshop on Bioenergy-2019, IIT Kharagpur - (2019)
• Direct bioethanol production in microalgae: A genetic engineering approach Saha S., Dutta A. , Ghosh S. K., Maiti M. K. By DBT National Workshop on Bioenergy-2018, IIT Roorkee - (2018)
Conferences
• Improved in vitro regeneration of sweet pearl millet Pennisetum glaucum (L.) Roy S., Sarkar S. , Ghosh S. K. By International Conference on Trends in Plant Science and Agrobiotechnology (ICTPA-2019) - (2019)
• Functionalized filter paper-based 3D liver model in vitro drug screening applications Agarwal T., Maiti T. K., Ghosh S. K. By 18th European Congress on Biotechnology (ECB 2018) - (2018)
• Drug resistance to parasitic diseases Ghosh S. K. By 2nd Intl. conference on Contemperoray Antimicrobial Research 65-65 (2018)
• Effect of hydrophobe content in PEG based polymeric micelles for delivery of S-(+)-camptothecin Laskar P., Saha B. , Ghosh S. K., Dey J. By International Conference on Rubber and Rubber-Like Materials (ICRRM 2013) - (2013)
Congress
• Is there any reproductive stage in the protozoan parasite Entamoeba? Ghosh S. K., Krishnan D. By 106 Indian Science Congress 50-50 (2019)
• Type IIA topoisomerase in Entamoeba is essential for its encystation Varghese S. S., Ghosh S. K. By The 43rd FEBS congress 205-205 (2018)
• Development of marker-free pod borer resistant Pigeon pea (Cajanus cajan) Sarkar S., Roy S. , Ghosh S. K. By The 43rd FEBS congress 172-172 (2018)
• Somatic embryogenesis of sweet pearl millet (Pennisetum glaucum), a rich source of cellulosic biomass Roy S., Sarkar S. , Ghosh S. K. By 18th European Congress on Biotechnology (ECB 2018) 91-91 (2018)
• Characterization of encystation-specific UDPN- acetylglucosamine transporter of Entamoeba Nayak S., Ghosh S. K. By The 43rd FEBS congress 371-371 (2018)
• Entamoeba cyst wall synthesis: A New insight Ghosh S. K., Nayak S. , Krishnan D. By 18th European Congress on Biotechnology 91-91 (2018)

Principal Investigator

• SILENCING OF GENE EXPRESSION IN PROTOZOAN PARASITE ENTAMOEBA HISTOLYTICA BY RNAI
• MOLECULAR EPIDEMIOLOGY AND IDENTIFICATION OF IMMUNODOMINANT ANTIGEN OF ENTAMOEBA IN AMOEBIC PATIENTS
• Characterization of encystation specific kinase(s) of entamoeba during encystations
• Generation of insect resistant sweet sorghum plant
• Expression of recombinant enzymes and green fluorescent protein with chitin binding domain of entamoeba histolytica lectins
• DEVELOPMENT OF POD BORER RESISTANT TRANSGENIC PIGEON PEA & CHICK PEA.
• Evaluation of the applicability of a dominant nuclear male sterlity system in rice for hybrid seed production
• Exploration and Identification of the Microbial and Chemical Hazards Present in Drinking-Water of Arunachal Pradesh Aiming to Supply the Safe Drinking Water
• Development of Indigenous Detection Tool for Entamoeba Histolytica from Stool Sample
• Development of Indigenous Detection Tool for Entamoeba Histolytica from Stool Sample

Co-Principal Investigator

• 28-2008 EXCHANGE TRAVEL PROGRAM - BIOFUEL & HEALTHCARE BIOTECH BETWEEN UNIVERSITY OF CALIFORNIA, BERKELEY AND IIT KHARAGPUR
• CHARACTERIZATION OF SILK PROTEIN SERICIN FROM INDIAN TROPICAL TASAR AND MUGA SILK
• Development of Bioactive 3D Scaffold with Nano/Micro Hierchy for Bone Tissue Engineering Through Combinatorial Approach
• DEVELOPMENT OF SILK PROTEINS BASED BIOMATERIALS
• EVALUATION OF POTENTIAL APPLICATIONS IN DRUG DELIVERY OF SOME NOVEL PH RESPONSIVE, BIOCOMPATIBLE AND BIOGRADABLE HYDROPHOBICALLY MODIFIED POLYMERS
• Molecular characterization of leptin in Indian major carps
• NORTH EASTERN ORIGIN SILK PROTEIN BASED MATRICES & NANO/MICRO PARTICLES FOR BIOMEDICAL APPLICATIONS.
• SILK PROTEIN / BLEND MATRICS IN TISSUE ENGINEERING & BIOTECHNOLOGICAL APPLICATIONS
• STUDIES ON MAGNETIC NANOPARTICLE ASSISTED HYPERTHERMIA ACTIVATION OF ENEDIYNES IN CANCER CELLS