Energy Science and Engineering

• Early Career Research Award
• Faculty Excellence Award 2020
• Eli Lilly Outstanding Thesis Award
• Prof B.H. Iyer Gold Medal IISc
• Ramalingaswami Fellow, DBT

Educational Package
• Metabolic Engineering Ghosh A., Sar P. By - (2023)
• Metabolic Engineering Sar P., Ghosh A. By - (2021)
Journal
• Pretreatment of Hevea Latex by Sorbitol: Improving the Efficacy of Silica Dispersion by a Biomimetic Approach Bera A., Manna B. , D. , Ganguly D. , Amarnath K. P., Nanda S. , Ghosh A. , Chattopadhyay S. By ACS Applied Polymer Materials 5 441-451 (2023)
• Recent advances in machine learning applications in metabolic engineering Patra P., R D. B., Kundu P. , Das M. , Ghosh A. By Biotechnology Advances 62 108069- (2023)
• Molecular insights into dissolution of lignin bunch in ionic liquid-water mixture for enhanced biomass conversion Radhakrishnan R., Manna B. , Ghosh A. By Renewable Energy 206 47-59 (2023)
• Genome-scale community modeling for deciphering the inter-microbial metabolic interactions in fungus-farming termite gut microbiome Kundu P., Ghosh A. By Computers in Biology and Medicine 154 106600- (2023)
• In-silico identification of critical residues in the mannose-transfer mechanism of phosphatidyl-myo-inositol mannosyltransferase B Bhattacharje G., Ghosh A. , Das A. K. By Biochemical and Biophysical Research Communications 621 14-19 (2022)
• In-silico screening and in-vitro assay show the antiviral effect of Indomethacin against SARS-CoV-2 Chakraborty R., Bhattacharje G. , Baral J. , Manna B. , Mullick J. , Mathapati B. S., Abraham P. , J M. , Hasija Y. , Ghosh A. , Das A. K. By Computers in Biology and Medicine 147 105788- (2022)
• Bacterial species metabolic interaction network for deciphering the lignocellulolytic system in fungal cultivating termite gut microbiota Kundu P., Mondal S. , Ghosh A. By Biosystems 221 104763- (2022)
• Thin films of functionalized carbon nanotubes support long-term maintenance and cardio-neuronal differentiation of canine induced pluripotent stem cells Mondal T., Das K. , Singh P. , Natarajan M. , Manna B. , Ghosh A. , Singh P. , Saha S. , Dhama K. , Dutt T. , Bag S. By Nanomedicine: Nanotechnology, Biology and Medicine 40 102487- (2022)
• Solvent Induced Conformational Changes for the Altered Activity of Laccase: A Molecular Dynamics Study Radhakrishnan R., Manna B. , Ghosh A. By Journal of Hazardous Materials 423 127123- (2022)
• Understanding the biomass conversion processes of bovine gut microbiota through community-wide metabolic interaction network Mondal S., Kundu P. , Ghosh A. By Bioresource Technology Reports 17 100989- (2022)
• Understanding the Mannose Transfer Mechanism of Mycobacterial Phosphatidyl-myo-inositol Mannosyltransferase A from Molecular Dynamics Simulations Bhattacharje G., Ghosh A. , Das A. K. By ACS Omega 7 19288-19304 (2022)
• Metagenome-scale community metabolic modelling for understanding the role of gut microbiota in human health Beura S., Kundu P. , Das A. K., Ghosh A. By Computers in Biology and Medicine 149 105997- (2022)
• A review on co-culturing of microalgae: A greener strategy towards sustainable biofuels production Ray A., Nayak M. , Ghosh A. By Science of The Total Environment 802 149765- (2022)
• Recent advancements in the ionic liquid mediated lignin valorization for the production of renewable materials and value-added chemicals Radhakrishnan R., Patra P. , Das M. , Ghosh A. By Renewable and Sustainable Energy Reviews 149 111368- (2021)
• Recent Advances in Systems and Synthetic Biology Approaches for Developing Novel Cell-factories in Non-Conventional Yeasts Patra P., Das M. , Kundu P. , Ghosh A. By Biotechnology Advances 47 107695- (2021)
• Molecular Insight into glucose induced conformational change to investigate uncompetitive inhibition of GH1 beta-glucosidase Manna B., Ghosh A. By ACS Sustainable Chemistry & Engineering 9 1613-1624 (2021)
• Role of Conformational Change and Glucose Binding Sites in the Enhanced Glucose Tolerance of Agrobacterium tumefaciens 5A GH1 -Glucosidase Mutants Goswami S., Manna B. , Chattopadhyay K. , Ghosh A. , Datta S. By Journal of Physical Chemistry B 125 9402-9416 (2021)
• Understanding the conformational change and inhibition of hyperthermophilic GH10 xylanase in ionic liquid Manna B., Ghosh A. By Journal of Molecular Liquids 332 115875- (2021)
• Understanding the Dissolution of Softwood Lignin in Ionic Liquid and Water Mixed Solvents Manna B., Ghosh A. By International Journal of Biological Macromolecules 182 402-412 (2021)
• Genome Scale-Differential Flux Analysis reveals deregulation of lung cell metabolism on SARS Cov2 infection Nanda P., Ghosh A. By PLoS Computational Biology 17 e10088- (2021)
• Reconstruction and analysis of genome-scale metabolic model of weak Crabtree positive yeast Lachancea kluyveri Nanda P., Patra P. , Das M. , Ghosh A. By Scientific Reports 10: 16314- (2020)
• Structure and dynamics of ionic liquid tolerant hyperthermophilic endoglucanase Cel12A from Rhodothermus marinus Manna B., Ghosh A. By RSC Advances 10 7933-7947 (2020)
• An allosteric hot spot in the tandem-SH2 domain of ZAP-70 regulates T-cell signaling Gangopadhyay K., Manna B. , Roy S. , Kumari . , Debnath O. , Chowdhury S. , Ghosh A. , Das R. By Biochemical Journal 477 1287-1308 (2020)
• Metabolic engineering for enhancing microbial biosynthesis of advanced biofuels Das M., Patra P. , Ghosh A. By Renewable and Sustainable Energy Reviews 119 109562- (2020)
• Dissolution of Cellulose in Ionic Liquid and water mixtures as revealed by Molecular Dynamics Simulations Manna B., Ghosh A. By Journal of Biomolecular Structure and Dynamics 37 3987-4005 (2019)
• Species-wide Metabolic Interaction Network for Understanding Natural Lignocellulose Digestion in Termite Gut Microbiota Kundu P., Manna B. , Majumder S. , Ghosh A. By Scientific Reports 9 16329- (2019)
• Dynamic Studies on Intrinsically Disordered Regions of Two Paralogous Transcription Factors Reveal Rigid Segments with Important Biological Functions Maiti S., Acharya B. , Sheersh Boorla V. , Manna B. , Ghosh A. , De S. By Journal of Molecular Biology 431 1353-1369 (2019)
• Single-molecule force-unfolding of titin I27 reveals a correlation between the size of the surrounding anions and its mechanical stability Muddassir M., Manna B. , Singh P. , Singh S. , R. , Ghosh A. , Sharma D. By Chemical Communications 54 9635-9638 (2018)
• Molecular and structural bases of interaction between extracellular domains of nectin-2 and N-cadherin Duraivelan K., A. J., Ghosh A. , Samanta D. By Proteins: Structure, Function, and Bioinformatics 86 1157-1164 (2018)
• Engineering high-level production of fatty alcohols by Saccharomyces cerevisiae from lignocellulosic feedstocks D L., Ghosh A. , Runguphan W. , Wehrs M. , Xu F. , Konzock O. , Dev I. , Nhan M. , Gin J. , Reider A. , Petzold C. , Singh S. , Simmons B. , Mukhopadhyay A. , García H. , Keasling J. By Metabolic Engineering 42 115-125 (2017)
• The JBEI quantitative metabolic modeling library (jQMM): a python library for modeling microbial metabolism Birkel G. W., Ghosh A. , Kumar V. S., Weaver D. , Ando D. , Backman T. W., Arkin A. P., Keasling J. D., Martin H. G. By BMC Bioinformatics 18 205-216 (2017)
• 13C Metabolic Flux Analysis for Systematic Metabolic Engineering of S. cerevisiae for Overproduction of Fatty Acids Ghosh A., Ando D. , Gin J. , Runguphan W. , Denby C. , Wang G. , Baidoo E. E., Shymansky C. , Keasling J. D., Martín H. G. By Frontiers in Bioengineering and Biotechnology 4(76) 1-10 (2016)
• Systems and Synthetic Biology for the Microbial Production of Biofuels Ghosh A. By Current Metabolomics 4(1) 5-13 (2016)
• The Combined Effects of Arbuscular Mycorrhizal Fungi (AMF) and Lead (Pb) Stress on Pb Accumulation, Plant Growth Parameters, Photosynthesis, and Antioxidant Enzymes in Robinia pseudoacacia L Yang Y., Han X. , Liang Y. , Ghosh A. , Chen J. , Tang M. By PLoS One 10(12) - (2016)
• The roles of arbuscular mycorrhizal fungi (AMF) in phytoremediation and tree-herb interactions in Pb contaminated soil Yang Y., Liang Y. , Han X. , Chiu T. , Ghosh A. , Chen H. , Tang M. By Scientific Reports 6 - (2016)
• Assessment of arbuscular mycorrhizal fungi status and heavy metal accumulation characteristics of tree species in a lead-zinc mine area: potential applications for phytoremediation Yang Y., Liang Y. , Ghosh A. , Song Y. , Chen H. , Tang M. By Environmental Science and Pollution Research 22 13179-13193 (2015)
• A 13C-based method for metabolic flux measurement and prediction in genome-scale models Martín H., Kumar V. , Weaver D. , Ghosh A. , Chubukov V. , Arkin A. , Keasling J. By PLoS Computational Biology 11 - (2015)
• Community structure of arbuscular mycorrhizal fungi associated with Robinia pseudoacacia in uncontaminated and heavy metal contaminated soils Yang Y., Song Y. , Schellerd H. , Ghosh A. , Ban Y. , Chen H. , Tang M. By Soil Biology and Biochemistry 86 146-158 (2015)
• A peptide-based method for 13C metabolic flux analysis in microbial communities Ghosh A., Nilmeier J. , Weaver D. , Adams P. , Keasling J. , Mukhopadhyay A. , Petzold C. , Martín H. By PLoS Computational Biology 10 - (2014)
• Allosteric communication in Cysteinyl tRNA Synthetase: A network of direct and indirect readout Ghosh A., Sakaguchi R. , Liu C. , Vishveshwara S. , Hou Y. By Journal of Biological Chemistry 286 37721-31 (2011)
• Genome-scale Consequences of Cofactor Balancing in Engineered Pentose Utilization Pathways in Saccharomyces Ghosh A., Zhao H. , Price N. By PLoS One 6 - (2011)
• Allostery and conformational free energy changes in human tryptophanyl-tRNA synthetase from essential dynamics and structure networks Bhattacharyya M., Ghosh A. , Hansia P. , Vishveshwara S. By Proteins: Structure, Function, and Bioinformatics 78 506-17 (2010)
• Intra and Inter molecular communications through Protein Structure Network Vishveshwara S., Ghosh A. , Hansia P. By Current Protein Peptide Science 10 146-160 (2009)
• Ligand dependent Intra and Inter subunit Communication in Human Tryptophanyl tRNA Synthetase as Deduced from the Dynamics of Structure Networks Hansia P., Ghosh A. , Vishveshwara S. By Molecular BioSystems 5 1860-72 (2009)
• Variations in clique and community patterns in protein structures during allosteric communication: Investigation of dynamically equilibrated structures of methionyl tRNA synthetase complexes Ghosh A., Vishveshwara S. By Biochemistry 7 11398-407 (2009)
• A study of Communication Pathways in Methionyl tRNA Synthetase by Molecular Dynamics Simulations and Structure Network analysis Ghosh A., Vishveshwara S. By Proceedings of the National Academy of Sciences of the United States of America 104 15711-1576 (2007)
• Dynamics of Lysozyme Structure Network: Probing the process of Unfolding Ghosh A., Brinda K. , Vishveshwara S. By Biophysical Journal 92 2523-2535 (2007)
Book Chapter/Section
• Biofuel production from renewable feedstocks: Progress through metabolic engineering Das M., Sarnaik A. , Patra P. , Varman A. M., Ghosh A. By Current Developments in Biotechnology and Bioengineering 417-448 (2022)
• Insight into Various Conventional Physical and Chemical Methods for the Pretreatment of Lignocellulosic Biomass Manna B., Das M. , Patra P. , Ghosh A. By Thermochemical and Catalytic Conversion Technologies for Future Biorefineries 31-57 (2022)
• Laccase-mediated Pretreatment of Lignocellulosic Biomass: Current Status and Future Prospects Radhakrishnan R., Shridhar B. , Ghosh A. By Enzymes in the Valorization of Waste 51-83 (2022)
• Overview of the Mechanism of Hydrolytic Enzymes and Their Application in Waste Treatment Patra P., Das M. , Manna B. , Ghosh A. By Enzymes in the Valorization of Waste 61-89 (2022)
• Recycling of Multiple Organic Solid Wastes into Biogas via Anaerobic Digestion Hajinajaf N., Das M. , Patra P. , Ghosh A. M., Varman A. M. By Production of Biofuels and Chemicals from Sustainable Recycling of Organic Solid Waste 173-204 (2022)
Conferences
• Community-wide metabolic interaction network for deciphering the plant biomass degradation potential of bovine gut microbiota Mondal S., Kundu P. , Ghosh A. By Biological Engineering Society Conference, 2022 - (2022)
• Understanding the Stability of Endoglucanase in Ionic Liquid-water Binary Mixtures by Molecular Dynamics Simulation Manna B., Ghosh A. By 43rd Indian Biophysical Society Meeting - (2019)
• Species-wide Metabolic Interaction Network for Understanding Natural Lignocellulose Digestion in Termite Gut Microbiota Kundu P., Manna B. , Ghosh A. By Biological Engineering Society Conference (BECON-2019) - (2019)
• Genome scale metabolic network reconstruction of Spirochaeta cellobiosiphila Manna B., Ghosh A. By NextGen Genomics, Biology, Bioinformatics and Technologies Conference 134- (2017)
• Metabolic engineering of yeast to produce fatty acid derived fuels and chemical Ghosh A. By Annual Meeting of the Indian Biophysical Society - (2016)
• Dissolution of Cellulose with Ionic Liquid/Water Mixture: A Molecular Dynamics Study Manna B., Ghosh A. By 21st Century Energy Needs: Materials, Systems and Applications 2016 - (2016)
• 13C Metabolic Flux Analysis for systematic metabolic engineering of yeast to produce fatty acid derived fuels and chemical Ghosh A. By 11th International Conference of the metabolomics society - (2015)
• 13C Metabolic Flux Analysis for Metabolic Engineered Yeast Strains for Production of Fatty Acids Ghosh A. By Conference on Constraint-Reconstruction and Analysis - (2014)
• Integrated Probabilistic Regulatory and Metabolic Network Analysis of Saccharomyces Cerevisiae for Biochemical Production Ghosh A. By AIChE annual meeting 2010 - (2010)
• In silico and experimental studies of cofactor balance in the engineered pentose sugar utilization pathways in Saccharomyces cerevisiae Ghosh A. By AIChE annual meeting 2009 - (2009)
• Variation in clique community patterns during allosteric communication in proteins Ghosh A. By 9th International Conference on Systems Biology - (2008)
• Modeling and molecular dynamics simulation of tRNA bound Methionine tRNA synthetase Ghosh A. By 'International Conference on Bioinformatics-2006 - (2006)
• Dynamics of t-RNA Synthetases Ghosh A. By 21st International t-RNA Workshop - (2005)

Principal Investigator

• 13C Based metabolic flux Analysis & Metabolic Engineering of Yeast for Biodiesel Production
• Metabolic Engineering of Yeast for free Fatty Acids Using CRISPR/Cas9 Platform
• Metabolic Engineering of Yeast Strains that Efficiently Utilizes C5/C6 Sugars for Production of Biofuels

Co-Principal Investigator

• Enhanced 2G Bioethanol Production through Improved Cellulolytic Activities of Filamentous Fungi through Metabolic and Genetic Engineering Strategies
• Pilot Scale Production of Ethanol from Lignocellulosic Feedstock: A Technological Challenge - UAY_I_IITKGP_020
• Pilot Scale Production of Ethanol from Lignocellulosic Feedstock: A Technological Challenge - UAY_I_IITKGP_020
• Pilot Scale Production of Ethanol from Lignocellulosic Feedstock: A Technological Challenge - UAY_I_IITKGP_020