Bio Science

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Journal
• Heterophilic recognition between E-cadherin and N-cadherin relies on same canonical binding interface as required for E-cadherin homodimerization Dash S., Duraivelan K., Hansda A., Kumari P., Chatterjee S., Mukherjee G., Samanta D. By Archives of Biochemistry and Biophysics 727 - (2022)
• High-resolution crystal structure of LpqH, an immunomodulatory surface lipoprotein of Mycobacterium tuberculosis reveals a distinct fold and a conserved cleft on its surface Chatterjee S., Kundapura S.V., Basak A.J., Mukherjee D., Dash S., Ganguli N., Das A.K., Mukherjee G., Samanta D., Ramagopal U.A. By International Journal of Biological Macromolecules 210 494-503 (2022)
• Cadherin-mediated host-pathogen interactions Dash S., Duraivelan K. , Samanta D. By Cell Microbiol 23 1-10 (2021)
• Emerging roles of the nectin family of cell adhesion molecules in tumour-associated pathways Duraivelan K., Samanta D. By Biochimica et Biophysica Acta - Reviews on Cancer 1876 - (2021)
• Immunoglobulin-fold containing bacterial adhesins: molecular and structural perspectives in host tissue colonization and infection Chatterjee S., Basak A. J., Nair A. V., Duraivelan K. , Samanta D. By FEMS Microbiol Lett 368 1-14 (2021)
• Cryptic association of B7-2 molecules and its implication for clustering Lankipalli S., Mahadeva Swamy H.S., Selvam D., Samanta D., Nair D., Ramagopal U.A. By Protein Science 30 1958-1973 (2021)
• An evolutionarily conserved charged residue dictates the specificity of heterophilic interactions among nectins Duraivelan K., Dash S. , Samanta D. By Biochem Biophys Res Commun 534 504-510 (2021)
• Tracing the Evolution of Nectin and Nectin-Like Cell Adhesion Molecules Duraivelan K., Samanta D. By Scientific Reports 10 9434-9444 (2020)
• Structural Insights into N-terminal IgV Domain of BTNL2, a T Cell Inhibitory Molecule, Suggests a Non-canonical Binding Interface for Its Putative Receptors Basak A. J., Maiti S. , Hansda A. , Mahata D. , Duraivelan K. , Kundapura . V., Lee . , Mukherjee G. , De S. , Samanta D. By Journal of Molecular Biology 432 5938-5950 (2020)
• Genetically modified hematopoietic stem/progenitor cells that produce IL-10-secreting regulatory T cells. Ng S. L., Leno-duran E. , Samanta D. , Almo S. C., Strominger J. L. By Proc Natl Acad Sci USA 116(7):2634-2639. 2634-2639 (2019)
• Molecular and structural bases of interaction between extracellular domains of nectin-2 and N-cadherin. Duraivelan K., Basak A. J., Ghosh A. , Samanta D. By Proteins 86 1157-1164 (2018)
• Structural, mutational and biophysical studies reveal a canonical mode of molecular recognition between immune receptor TIGIT and nectin-2. Samanta D., Guo H. , Rubinstein R. , Ramagopal U. , Almo S. By Mol Immunol 81 151-159 (2017)
• A Possible Role of the Full-Length Nascent Protein in Post-Translational Ribosome Recycling Das D., Samanta D. , Bhattacharyay A. , Basu A. , Das A. , Ghosh J. , Chakrabarti A. , Dasgupta C. By PLoS One 12 e0170-e01703 (2017)
• Nectin family of cell-adhesion molecules: structural and molecular aspects of function and specificity Samanta D., Almo S. By Cell Mol Life Sci 72 645-658 (2015)
• Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion Samanta D, Ramagopal UA, Rubinstein R, Vladimir V, Nathenson SG, Almo SC By Proc Natl Acad Sci USA 109 14836-14840 (2012)
• Identical RNA-protein interactions in vivo and in vitro and a scheme of folding the newly synthesized proteins by ribosomes. Das D., Samanta D. , Hassan S. , Das A. , Bhattacharyay A. , Dasgupta S. , Chakrabarti A. , Ghorai P. , Dasgupta C. By J Biol Chem 287 37508-37521 (2012)
• Structural and Functional Characterization of a Single-chain Peptide-MHC Molecule that Modulates Both Naive and Activated CD8+ T Cells Samanta D*, Mukherjee G*, Ramagopal UA, Chaparro RJ, Nathenson SG, DiLorenzo TP, Almo SC. (*equally contributed) By Proc Natl Acad Sci USA 108 13682-13687 (2011)
• Mechanism of ribosome assisted protein folding: a new insight into rRNA functions Samanta D*, Das A, Bhattacharya A, Basu A, Das D, DasGupta C*. (*corresponding author) By Biochem Biophys Res Commun 384 137-140 (2009)
• Protein folding by domain V of Escherichia coli 23S rRNA: specificity of RNA-protein interactions Samanta D, Mukhopadhyay D, Chowdhury S, Ghosh J, Pal S, Basu A, Bhattacharya A, Das A, Das D, DasGupta C By J Bacteriol 190 3344-3352 (2008)
• Protein folding following synthesis in vitro and in vivo: association of newly synthesized protein with 50S subunit of E. coli ribosome Basu A*, Samanta D*, Bhattacharya A, Das A, Das D, Dasgupta C. (*equally contributed) By Biochem Biophys Res Commun 366 592-597 (2008)
• In vitro protein folding by E. coli ribosome: unfolded protein splitting 70S to interact with 50S subunit. Basu A., Samanta D. , Dasgupta C. K. By Biochem Biophys Res Commun 366(2) 598-603 (2008)
Conferences
• Structural and dynamic investigations of murine BTNL2, an orphan T cell co-inhibitor Basak A. J., Maiti S. , Hansda A. , Mukherjee G. , De S. , Samanta D. By 27th conference of the National Magnetic Resonance Society (NMRS 2022) - (2022)
• Identification and characterization of novel macromolecular assemblies responsible for cell adhesion Dash S., Samanta D. By ASBMB 2022 Annual Meeting - (2022)
Congress
• The T Cell Inhibitory Molecule Butyrophilin Like-2 Shows Promiscuous Receptor Binding to Regulate Mucosal Immune Response Hansda A., Basak A. J., Biswas D. , Mahata D. , Samanta D. , Mukherjee G. By British Society of Immunology Congress 2021 - (2021)
Symposium
• Solution state structural and dynamic studies of mouse BTNL2, an orphan T cell coinhibitory molecule Basak A. J., Maiti S. , Hansda A. , Mahata D. , Lee W. , Mukherjee G. , De S. , Samanta D. By 33rd Annual Symposium of The Protein Society 152-152 (2019)

Principal Investigator

• Identification of Novel and Therapeutically Relevant Molecular Interactions Involving Immunoglobulin Superfamily Members
• Structure - Function Relationship and Engineering of Immunoglobulin Super - Family (IgSF) Proteins: from Mechanisms to Therapeutics

Co-Principal Investigator

• BTNL2, a Novel T Cell Coinhibitory Molecule, as a Therapeutic Target in Ulcerative Colitis