As chemists, we are intensely interested in the field of nucleic acid, and value in-depth investigation of the subject and its challenges.
We primarily focus on two topics.
G-quadruplex nucleic acid
Prebiotic chemistry
All projects typically require the involvement of synthetic organic chemistry, coordination chemistry, and nucleic acid chemistry.
For more information, Please visit our website: https://www.jashlab.org/
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Single Nucleotide Translation without Ribosomes Jash B., Tremmel P. , Jovanovic D. , Richert C. By Nature Chemistry 13 751-757 (2021)
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A stable Zinc(II)-mediated base pair in parallel-stranded DNA duplex Jash B., Mueller J. By Journal of Inorganic Biochemistry 186 301-306 (2018)
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Stable Copper(I)-mediated base pair in DNA Jash B., Mueller J. By Angewandte Chemie International Edition 57 9524-9527 (2018)
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A metal-mediated base pair that discriminates between the canonical pyrimidine nucleobases Jash B., Scharf P. , Sandmann N. , Guerra C. F., Megger D. A., Mueller J. By Chemical Science 8 1337-1343 (2017)
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Templates direct the sequence-specific anchoring of the C-terminus of peptido RNAs Jash B., Richert C. By Chemical Science 11 3487-3494 (2020)
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Concomitant site-specific incorporation of Silver(I) and Mercury(II) ions into a DNA duplex Jash B., Mueller J. By Chemistry A European Journal 24 10636-10640 (2018)
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Metal-mediated base pairs: from characterization to application Jash B., Mueller J. By Chemistry A European Journal 23 17166-17178 (2017)
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Sequence-dependent duplex stabilization upon formation of a metal-mediated base pair Scharf P., Jash B. , Kuriappan J. A., Waller M. P., Mueller J. By Chemistry A European Journal 22 295-301 (2016)
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Enantiospecific formation of metal-mediated base pair inside a DNA duplex Jash B., Neugebauer J. , Mueller J. By Inorganica Chimica Acta 452 181-187 (2016)
Principal Investigator
- ROLE OF METAL IONS IN THE SYNTHESIS OF THE EARLY FORM OF BIOMOLECULES
Ph. D. Students
Debarati Bhattacharya
Area of Research: G-quadruplex nucleic acid
Manick Mistri
Area of Research: Prebiotic Chemistry
Nirmal Pal
Area of Research: Prebiotic Chemistry
