Our research group works at the interface of chemistry, biology and material sciences with light as an important tool. We are interested in designing new fluorescent Photoremovable Protecting groups for controlled release of bioactive molecules. Recent research in our laboratory has focused on the following areas:
Controlled Drug delivery:
Real time monitoring Single component nano vehicle for image guided drug delivery
Di & Tri modal Combination Therapy
Micro environment assisted real time monitoring based drug delivery
Photocatalysis for Organic transformations
Organic Reactive intermediates
Self assembled Smart Materials
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Perylene-3-ylmethanol: Fluorescent Organic Nanoparticles as a Single-Component Photoresponsive Nanocarrier with Real-Time Monitoring of Anticancer Drug Release Avijit Jana, K. Sanjana P. Devi, Tapas K. Maiti, and N. D. Pradeep Singh By J. Am. Chem. Soc. 134 (18) 7656-7659 (2012)
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Photocaging of Single and Dual (Similar or Different) Carboxylic and Amino Acids by Acetyl Carbazole and its Application as Dual Drug Delivery in Cancer Therapy Pradeep N. D., Mandal M. , Venkatesh Y. , Rajesh Y. , Karthik D. , Chetan A. C., Jana D. By journal of organic chemistry 81 11168-11175 (2016)
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A p-HydroxyphenacylBenzothiazoleChlorambucil Conjugate as a Real-Time-Monitoring Drug-Delivery System Assisted by Excited-State Intramolecular Proton Transfer Barman S., Mukhopadhyay S. ., Biswas S. , Nandi S. , Gangopadhyay M. , Dey S. , Anoop A. , Pradeep Singh N. D. By Angewandte Chemie International Edition 55 4194-4198 (2016)
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Bimane: A Visible Light Induced Fluorescent Photoremovable Protecting Group for the Single and Dual Release of Carboxylic and Amino Acids Pradeep N. D., Chaudhuri A. , Venkatesh Y. , Behara . K. By Organic Letters 19 1598-1601 (2017)
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Light triggered uncaging of hydrogen sulfide (H2S) with real-time monitoring. Venkatesh Y., J D. , Venkatesh A. , Karmakar A. , Maiti T. K., Pradeep Singh N. D. By Chem. Commun. - (2018)
Principal Investigator
- Design and Development of Near Infrared Light Responsive Drug Delivery Systems for Operating in Phototherapeuric Window Based on NIR and Two Photon Chromophores for Cancer Treatment
- Light Induced Gasotransmitter Donors for Spatio-temporal Combinatorial Release of Gaseous Molecules for Bacterial Biofilm Eradication
Ph. D. Students
Antara Sikder
Area of Research: organic photochemistry
Bhaskara Rao Pinninti
Area of Research: organic photochemistry
Malabika Bera
Area of Research: organic Photochemistry
Mamata Ojha
Area of Research: organic Photochemistry
Maniklal Shee
Area of Research: Organic Photochemistry
Saugat Mondal
Area of Research: organic Photochemistry
Soumik Chatterjee
Area of Research: Organic photochemistry
Souvik Ray
Area of Research: organic Photochemistry
Subham Pal
Area of Research: organic Photochemistry
Suchhanda Biswas
Area of Research: organic Photochemistry
Yasin Nuree
Area of Research: Synthetic Organic Chemistry