IITKGP

Narayan Dhuleep Pradeep Singh

Professor

Chemistry

+91-3222-282324

ndpradeep@chem.iitkgp.ac.in

Research Areas

  • Design and Development of FPRPG.
  • Development of One and Two-Photon PRPG.
  • Organic Nanocarrier for Image Guided DDS
  • PRPG for release of Gasotransmitters.
  • Photocatalysis for Organic Synthesis.

Our research group works at the interface of chemistry, biology and material sciences with light as an important tool. We are interested in designing new fluorescent Photoremovable Protecting groups for controlled release of bioactive molecules. Recent research in our laboratory has focused on the following areas: 

Controlled Drug delivery:

Real time monitoring Single component nano vehicle for image guided drug delivery

Di & Tri modal Combination Therapy

Micro environment assisted real time monitoring based drug delivery

    Photocatalysis for Organic transformations

    Organic Reactive intermediates

    Self assembled Smart Materials

    • Perylene-3-ylmethanol: Fluorescent Organic Nanoparticles as a Single-Component Photoresponsive Nanocarrier with Real-Time Monitoring of Anticancer Drug Release Avijit Jana, K. Sanjana P. Devi, Tapas K. Maiti, and N. D. Pradeep Singh By J. Am. Chem. Soc. 134 (18) 7656-7659 (2012)
    • Photocaging of Single and Dual (Similar or Different) Carboxylic and Amino Acids by Acetyl Carbazole and its Application as Dual Drug Delivery in Cancer Therapy Pradeep N. D., Mandal M. , Venkatesh Y. , Rajesh Y. , Karthik D. , Chetan A. C., Jana D. By journal of organic chemistry 81 11168-11175 (2016)
    • A p-HydroxyphenacylBenzothiazoleChlorambucil Conjugate as a Real-Time-Monitoring Drug-Delivery System Assisted by Excited-State Intramolecular Proton Transfer Barman S., Mukhopadhyay S. ., Biswas S. , Nandi S. , Gangopadhyay M. , Dey S. , Anoop A. , Pradeep Singh N. D. By Angewandte Chemie International Edition 55 4194-4198 (2016)
    • Bimane: A Visible Light Induced Fluorescent Photoremovable Protecting Group for the Single and Dual Release of Carboxylic and Amino Acids Pradeep N. D., Chaudhuri A. , Venkatesh Y. , Behara . K. By Organic Letters 19 1598-1601 (2017)
    • Light triggered uncaging of hydrogen sulfide (H2S) with real-time monitoring. Venkatesh Y., J D. , Venkatesh A. , Karmakar A. , Maiti T. K., Pradeep Singh N. D. By Chem. Commun. - (2018)

    Principal Investigator

    • Design and Development of Near Infrared Light Responsive Drug Delivery Systems for Operating in Phototherapeuric Window Based on NIR and Two Photon Chromophores for Cancer Treatment
    • Light Induced Gasotransmitter Donors for Spatio-temporal Combinatorial Release of Gaseous Molecules for Bacterial Biofilm Eradication

    Ph. D. Students

    Antara Sikder

    Area of Research: organic photochemistry

    Bhaskara Rao Pinninti

    Area of Research: organic photochemistry

    Malabika Bera

    Area of Research: organic Photochemistry

    Mamata Ojha

    Area of Research: organic Photochemistry

    Maniklal Shee

    Area of Research: Organic Photochemistry

    Saugat Mondal

    Area of Research: organic Photochemistry

    Soumik Chatterjee

    Area of Research: Organic photochemistry

    Souvik Ray

    Area of Research: organic Photochemistry

    Subham Pal

    Area of Research: organic Photochemistry

    Suchhanda Biswas

    Area of Research: organic Photochemistry

    Yasin Nuree

    Area of Research: Synthetic Organic Chemistry